NAD+ and Aging: Why Your Cellular Energy Declines Over Time

What NAD+ does

NAD+ is a coenzyme found in every cell, essential to the mitochondrial reactions that produce cellular energy and to enzymes involved in cellular maintenance and metabolism (Covarrubias et al., 2021).

Why it declines

Research indicates NAD+ availability tends to fall as we age, driven by a mix of reduced production and increased consumption in the body. Lower NAD+ is associated with the reduced cellular energy capacity many people notice over time.

Supporting healthy NAD+ levels is where precursors like NMN come in: by supplying the direct building block, NMN gives your cells more raw material to maintain NAD+ (Rajman, Chwalek & Sinclair, 2018).

What you can do

Exercise, sleep, and not over-consuming alcohol all support NAD+ metabolism. A well-dosed NMN supplement in a delivery format built to survive digestion is a studied way to add direct precursor support.

Frequently asked questions

Does NAD+ decline with age?

Research indicates NAD+ availability tends to fall with age, which is linked to reduced cellular energy capacity.

Can you raise NAD+ naturally?

Exercise, quality sleep, and moderating alcohol support NAD+ metabolism. Precursors like NMN add direct building-block support.

How does NMN help NAD+?

NMN is a direct precursor your body converts into NAD+, supplying raw material to support healthy levels.

References

• Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules. Cell Metabolism, 2018. PubMed
• Covarrubias AJ, et al. NAD+ metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology, 2021. PubMed
• Yoshino J, Baur JA, Imai SI. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metabolism, 2018. PubMed
• Irie J, et al. Effect of oral administration of nicotinamide mononucleotide in healthy men. Endocrine Journal, 2020. PubMed

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary.